University of Colorado Cancer Center Tissue Culture & Monoclonal Antibody Shared Core Service

The Tissue Culture and Monoclonal Antibody Core, located on the Anschutz Medical Campus, offers services to UCCC members, other academic investigators and private companies. We have more than 10 years of experience with protein production in the baculovirus system cell fusion, as well as developing new monoclonal antibodies and small- to large-scale culture of a wide range of cell lines.

Services We Offer

Custom Hybridoma Services

• Construction of new hybridomas
• In vitro production of monoclonal antibodies from existing hybridomas

Custom Baculovirus Services

• Construction of recombinant virus
• Amplification and titering of recombinant baculovirus stocks
• Protein production in insect cells

Cell Line Repository

• >150 cancer cell lines, including 51 different lung cancer cell lines and 11 breast cancer cell lines

On-Site Culture Media/Serum Supply Center

Offered to all UCCC and UC Denver investigators at prices substantially below list

• Liquid cell culture medium from Invitrogen and HyClone
• Supplements
• Serum from HyClone