Tissue Procurement Shared Core Service

The Tissue Procurement Core provides University of Colorado Cancer Center members and other funded researchers with well-characterized human tumors and materials derived from human tumors for research in human cancer. Our organ-based pathology subspecialists contribute anatomic expertise to organizing collection protocols and verify histopathological classification of specimens we collect.

We provide investigators with IRB-approved protocols and pathologiy subspecialist collaborators with:

  • frozen tissue fragments
  • tissue sections
  • DNA
  • RNA
  • cells purified by microdissection from tumors, preneoplastic lesions and matched normal control tissue

Services We Provide

  • Tissue grossing
  • Tissue processing
  • Tissue embedding
  • Cutting paraffin and frozen sections
  • HE staining
  • Cell line fixation, including cell pallet creation
  • Tissue array block creation from donor blocks
  • Tissue array cutting
  • Special cutting and staining sections for microdissection
  • Immunohistochemistry staining, including antibody standardizations
  • Tunnel assay staining
  • Some histology special stains, upon request

Turnaround time depends on the specimen or project. Please contact Jenny Caputo for a time estimate for your project.

Equipment

  • Tissue-Tek Vacuum Infiltration Processor
  • Microm Tissue Embedding Unit
  • Microm Paraffin Microtome
  • Shandon Varistain Slide Stainer
  • Dako Autostainer Automated Immunostaining System
  • Biocare Medical Decloaking Chamber for Antigen Retrieval
  • Fisher Tissue Prep Flotation Bath for Paraffin Sections
  • Thermo Shandon Slide Heater-Oven
  • Fisher Isotemp 205 Water Bath for heating up reagents
  • Fisher Isotemp Table Top Oven for Reagent Incuvation
  • Forma Liquid Nitrogen Freezer with Inventory Storage System 

NCICC

Tissue Procurement

Location

Anschutz Medical Campus
Department of Pathology
RC1-South, Room 5400A
12801 E. 17th Ave.
Aurora, CO 80045

Shipping Address

UCCC Tissue Procurement Core
c/o Jennifer A. Caputo
Department of Pathology
Mail Stop 8104, PO Box 6511
Aurora, CO 80045-0508

Leadership & Staff

Wilbur Franklin, MD, PhD
Core Director
wilbur.franklin@ucdenver.edu
303-724-3080

Jennifer A. Caputo, BS
Tissue Banking Manager
jennifer.caputo@ucdenver.edu
Phone: 303-724-3092
Fax: 303-724-3096

Courier Service

Twice daily at 9:30 am and 2:30 pm
To/From 9th Ave. & Anschutz Campuses

9th Ave. Dropoff

Biomedical Research Building, Room 541
Call for door code

Anschutz Dropoff

RC1-South, Room 5400A