Metabolomics Core Publications
(updated 12/07)
The following publications were conducted in our Core and describe methodology and application of MRS-based metabolomics:
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Gottschalk S, Anderson N, Hainz C, Eckhardt SG, Serkova NJ: Imatinib (STI571)-mediated changes in glucose metabolism in human leukemia BCR-ABL positive cells. Clin Cancer Res 10: 6661-6668, 2004.
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Serkova NJ, Jackman M, Brown JL, Liu T, Hirose R, Roberts JP, Maher JJ, Niemann CU: Metabolic profiling of livers and blood from obese Zucker rats. J Hepatol 44: 956-962, 2006.
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Serkova NJ and Niemann CU: Pattern recognition and biomarker validation using quantitative 1H-NMR based metabolomics: A review. Expert Rev Mol Diagn 6: 717-731, 2006.
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Glunde K and Serkova NJ: Therapeutic targets and surrogate markers in choline phospholipid metabolism in cancer: A review. Pharmacogenomics 7: 1109-1123, 2006.
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Rudolph MC, McManaman JL, Phang TL, Anderson SM, Russell T, Kominsky DJ, Serkova NJ, Neville MC: Metabolic regulation in the lactating mouse: A milk lipid synthesizing machine. Physiol Genomics 28: 323-326, 2007.
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Serkova NJ, Zhang Y, Coatney JL, Hunter L, Wachs M, Niemann CU, Mandell SM: Early detection of graft failure using the blood metabolic profile of a liver recipient. Transplantation 83: 517-521, 2007.
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Serkova NJ, Rose JC, Epperson LE, Carey HV, Martin SL: Quantitative analysis of liver metabolites in three stages of the circannual hibernation cycle in 13-lined ground squirrels by NMR. Physiol Genomics 31: 15-24, 2007.
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Niemann CU and Serkova NJ: Biochemical mechanisms of nephrotoxicity: Application for metabolomics: A review. Exp Opin Drug Metab Toxicol 3: 527-544, 2007.
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Serkova NJ, Spratlin JL, Eckhardt SG: NMR-based metabolomics: Translational application and treatment of cancer: A review. Curr Opin Mol Ther 9: 572-585, 2007.
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Serkova NJ, Gamito EJ, Jones RH, O’Donnell C, Brown JL, Green S, Sullivan H, Hedlund T, Crawford ED: “The metabolites citrate, myo-inositol, and spermine are potential age-dependent markers of prostate cancer in human expressed prostatic secretions” to Prostate [in press].